Vitamin D is technically not a vitamin but rather can be considered to be a hormone.[1] Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and for many other biological effects.[2][3][1] In humans, the most important compounds in this group are vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol).[3][1][4]
The major natural source of vitamin D is synthesis of cholecalciferol in the lower layers of the epidermis of the skin, through a photochemical reaction of UVB light, from the sun exposure (specifically UVB radiation) or UVB lamps.[2] Cholecalciferol and ergocalciferol can be ingested from the diet and supplements.[2][3] Only a few foods, such as the flesh of fatty fish, naturally contain significant amounts of vitamin D.[3][5] In the U.S. and other countries, cow's milk and plant-derived milk substitutes are fortified with vitamin D, as are many breakfast cereals.[2] Mushrooms exposed to ultraviolet light contribute useful amounts of vitamin D2.[3] Dietary recommendations typically assume that all of a person's vitamin D is taken by mouth, because sun exposure in the population is variable and recommendations about the amount of sun exposure that is safe are uncertain in view of the skin cancer risk.[3]
Vitamin D from the diet, or from skin synthesis, is biologically inactive. It is activated by two protein enzyme hydroxylation steps, the first in the liver and the second in the kidneys.[2][4] Because vitamin D can be synthesized in adequate amounts by most mammals if they get enough sunlight, it is not essential and therefore is technically not a vitamin.[1] Instead it can be considered a hormone, with activation of the vitamin D pro-hormone resulting in the active form, calcitriol, which then produces effects via a nuclear receptor in multiple locations.[1]
Cholecalciferol is converted in the liver to calcifediol (25-hydroxycholecalciferol); ergocalciferol is converted to 25-hydroxyergocalciferol.[2] These two vitamin D metabolites (called 25-hydroxyvitamin D or 25(OH)D) are measured in serum to determine a person's vitamin D status.[6][7] Calcifediol is further hydroxylated by the kidneys and some of the immune system cells to form calcitriol (1,25-dihydroxycholecalciferol), the biologically active form of vitamin D.[8][9] Calcitriol circulates as a hormone in the blood, having a major role regulating the concentration of calcium and phosphate, and promoting the healthy growth and remodeling of bone.[2] Calcitriol also has other effects, including some on cell growth, neuromuscular and immune functions, and reduction of inflammation.[3]
Vitamin D has a significant role in calcium homeostasis and metabolism.[2] Its discovery was due to effort to find the dietary substance lacking in children with rickets (the childhood form of osteomalacia).[10] Vitamin D supplements are given to treat or to prevent osteomalacia and rickets.[2] The evidence for other health effects of vitamin D supplementation in vitamin D–replete individuals is inconsistent.[3] The effect of vitamin D supplementation on mortality is not clear, with one meta-analysis finding a small decrease in mortality in elderly people.[11] Except for the prevention of rickets and osteomalacia in high-risk groups, any benefit of vitamin D supplements to musculoskeletal or general health may be small.[12][13][14]
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nordic naturals vitamin d3 gummies
Individuals with certain medical conditions or taking specific medications should consult a healthcare provider before taking vitamin D3 supplements. Additionally, those with hypercalcemia or vitamin D toxicity should avoid additional supplementation.
The time it takes to feel better after taking vitamin D3 varies widely among individuals and depends on the specific health issues related to deficiency. Some may experience improvements in a few weeks, while others may take longer. Regular monitoring and patience are key.
D3 gummies supplement your daily vitamin D intake, assisting in maintaining strong bones, supporting immune function, and promoting overall health. They offer a tasty and convenient way to meet your vitamin D requirements.
The frequency of vitamin D3 supplementation depends on your individual needs and healthcare provider recommendations. It can range from daily to weekly, with dosing schedules tailored to your specific circumstances.
The appropriate number of D3 gummies to take depends on the specific product and its labeled dosage instructions. Typically, one or two gummies per day should provide the recommended dose of vitamin D3 for most individuals. However, it's essential to follow the product's guidance or consult a healthcare professional for personalized advice.
Individuals with vitamin D deficiencies, limited sun exposure, darker skin tones, or specific health conditions that affect vitamin D absorption may benefit from vitamin D3 supplementation. Consulting a healthcare provider can help determine if you have a need for supplementation.
While vitamin D3 is generally safe when taken within recommended doses, excessive intake can lead to side effects like nausea, vomiting, and kidney problems. It's important to adhere to dosage guidelines and seek medical advice if you have concerns.
Vitamin D3 is a specific form of vitamin D, often considered the active and more beneficial form for supplementation. Vitamin D can refer to either D2 (ergocalciferol) or D3 (cholecalciferol), with D3 being preferred for most purposes.
The frequency of vitamin D3 supplementation depends on your specific needs and healthcare provider recommendations. Daily or weekly dosing can both be effective, with weekly dosing often preferred for convenience and compliance.
Some individuals may experience sleep disturbances with high doses of vitamin D, but it's not a common side effect. Taking vitamin D3 earlier in the day or discussing any sleep concerns with a healthcare provider may help mitigate potential disruptions.
Vitamin D3 plays a role in overall well-being, and deficiency can lead to fatigue, but it doesn't directly provide energy boosts like caffeine. Maintaining adequate levels may support overall vitality and reduce feelings of tiredness.
After taking vitamin D3, it aids in the absorption of calcium, which is essential for strong bones and teeth. Additionally, it supports immune system function and may contribute to overall health and well-being. However, specific effects may vary among individuals.